Thousands of Americans Treated With Psilocybin in 2025
Published on 2026-03-28T19:34:00Z
In a new 4,000-word article, CNN tells the story of a retired appellate paralegal and grandmother in her early 70s who was treated for depression with psilocybin. CNN notes there's now retreats featuring psilocybin in a few countries — and while psilocybin is illegal under United States federal law, "In Oregon, 5,935 clients received psilocybin services through Oregon's state-regulated program in 2025." High doses of psilocybin are effective in treating depression, a growing body of research suggests, with promise for other conditions, like PTSD and addiction, said Dr. Albert Garcia-Romeu, associate director of the Center for Psychedelic and Consciousness Research at Johns Hopkins University... Some researchers suggest it disrupts entrenched traffic patterns in the brain or grows new neuron connections to change thinking. Others say the results from psilocybin could have to do with its anti-inflammatory effect, Garcia-Romeu said... Colorado became the second state to make psilocybin legal with a 2023 law and issued its first healing center" last year. A law adopted in New Mexico last year established that state's Medical Psilocybin Program, now in development... Psilocybin seems to be "knocking on the door of FDA approval," said Dr. Lynn Marie Morski, president of the Psychedelic Medicine Association, which educates health care providers on the therapeutic use of psychedelics so they can answer patients' questions through the lenses of clinical evidence and harm reduction. Psilocybin therapy first received a "breakthrough therapy" designation for treatment-resistant depression from the US Food and Drug Administration in 2018, and now psilocybin drug products are on track to be submitted to the FDA for possible approval in the not-too-distant future. While psilocybin is illegal under United States federal law, more states are creating their own paths for legal use under state laws.
Published on 2026-03-28T19:34:00Z
In a new 4,000-word article, CNN tells the story of a retired appellate paralegal and grandmother in her early 70s who was treated for depression with psilocybin. CNN notes there's now retreats featuring psilocybin in a few countries — and while psilocybin is illegal under United States federal law, "In Oregon, 5,935 clients received psilocybin services through Oregon's state-regulated program in 2025." High doses of psilocybin are effective in treating depression, a growing body of research suggests, with promise for other conditions, like PTSD and addiction, said Dr. Albert Garcia-Romeu, associate director of the Center for Psychedelic and Consciousness Research at Johns Hopkins University... Some researchers suggest it disrupts entrenched traffic patterns in the brain or grows new neuron connections to change thinking. Others say the results from psilocybin could have to do with its anti-inflammatory effect, Garcia-Romeu said... Colorado became the second state to make psilocybin legal with a 2023 law and issued its first healing center" last year. A law adopted in New Mexico last year established that state's Medical Psilocybin Program, now in development... Psilocybin seems to be "knocking on the door of FDA approval," said Dr. Lynn Marie Morski, president of the Psychedelic Medicine Association, which educates health care providers on the therapeutic use of psychedelics so they can answer patients' questions through the lenses of clinical evidence and harm reduction. Psilocybin therapy first received a "breakthrough therapy" designation for treatment-resistant depression from the US Food and Drug Administration in 2018, and now psilocybin drug products are on track to be submitted to the FDA for possible approval in the not-too-distant future. While psilocybin is illegal under United States federal law, more states are creating their own paths for legal use under state laws.
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