Male Fruit Fly Brain Trained to Play Doom Published on 2026-09-12T01:00:00Z Last week, Google announced that it managed to produce a detailed 3D reconstruction of an adult male fruit fly's brain and central nervous system. A few days later a software engineer at Coinbase said the fly brain was being trained to play the original Doom. "Each Doom frame stimulates sensory neurons," says Alex Wormuth. "Neural activity is mapped to game controls. Damage triggers a stimulus to two PPL101 dopamine cells as reinforcement." Since then, the digital brain model has been repurposed to control other games like Beat Saber and Super Mario 64. PC Gamer reports: You can even watch the fruit fly play in real time via Wormuth's website, and it not only shows the point of view in Doom, but can also show a third-person render of the fly going around Doom maps. As of the time of writing, the fly is on round 6385 and, well, it's not very good. Sorry, fly. But modders aren...
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