Skip to main content

Slashdot: Scientists Find Link Between Parkinson's Disease and the Appendix

Scientists Find Link Between Parkinson's Disease and the Appendix
Published on November 01, 2018 at 09:00AM
An anonymous reader quotes a report from Gizmodo: Scientists have found further evidence that the gut, or more specifically the appendix, might play a role in the development of Parkinson's disease. The international team of scientists reviewed two datasets, including a large registry from Sweden, and found that removal of the appendix was associated with a decreased risk of developing Parkinson's disease. They also found that the human appendix contains clumps of a protein called alpha-synuclein in a form associated with the disease. There's more work to be done, and the authors are not advocating that people preemptively remove their appendixes, but they hope that the research could provide a pathway towards treatment. The study found that of the 1,144,745 Swedes who did not have appendectomies, 1,608 had Parkinson's, but of the 551,003 who had, only 644 had Parkinson's. This is amounts to a 16.9% decrease in the odds of acquiring the disease -- but in absolutes, that's the difference between an 0.14 percent chance of acquiring the disease for those who hadn't gotten their appendix removed versus an 0.11 percent chance for those who had. The effect was also stronger in those living in rural areas, according to the study published today in Science Translational Medicine. The researchers also found that for those who had appendectomies at least 30 years before developing Parkinson's, the procedure was associated with a 3.6-year delay in disease onset. The appendix samples contained alpha-synuclein proteins and shortened and mis-folded alpha-synucleins like the ones found in people with Parkinson's disease. Professor Viviane Labrie from the Cancer of Neurodegenerative Science at the Van Andel Research Institute in Michigan suggests that the alpha-synucleins "can travel up the nerve that connects the G.I. tract to the brain." She added: "If it were to enter the brain, it can seed and spread from there and have neurotoxic effects that could eventually lead to Parkinson's disease."

Read more of this story at Slashdot.

Labels:

Comments

Post a Comment

Popular posts from this blog

Slashdot: AT&T Now Lets Customers Lock Down Account To Prevent SIM Swapping Attacks

AT&T Now Lets Customers Lock Down Account To Prevent SIM Swapping Attacks Published on July 02, 2025 at 01:30AM AT&T has launched a new Account Lock feature designed to protect customers from SIM swapping attacks. The security tool, available through the myAT&T app, prevents unauthorized changes to customer accounts including phone number transfers, SIM card changes, billing information updates, device upgrades, and modifications to authorized users. SIM swapping attacks occur when criminals obtain a victim's phone number through social engineering techniques, then intercept messages and calls to access two-factor authentication codes for sensitive accounts. The attacks have become increasingly common in recent years. AT&T began gradually rolling out Account Lock earlier this year, joining T-Mobile, Verizon, and Google Fi, which already offer similar fraud prevention features. Read more of this story at Slashdot.
Post a Comment
Read more

Slashdot: AT&T Outlines $250 Billion US Investment Plan To Boost Infrastructure In AI Age

AT&T Outlines $250 Billion US Investment Plan To Boost Infrastructure In AI Age Published on 2026-03-10T20:00:00Z AT&T plans to invest more than $250 billion over the next five years to expand U.S. telecom infrastructure for the AI age. The company says it will also hire thousands of technicians while partnering with AST SpaceMobile to extend coverage to remote areas. Reuters reports: Rapid adoption of artificial intelligence, cloud computing and connected devices has prompted telecom operators to invest heavily in fiber and 5G networks as they also seek to fend off intensifying competition from cable broadband providers. AT&T, which has about 110,000 employees in the U.S., said the new hires will help build and maintain its infrastructure. The outlay includes capital expenditure and other spending, the company said. The spending will focus on expanding its fiber and wireless networks, including accelerating deployment of fiber broadband, 5G home internet and satellite co...
Post a Comment
Read more

Slashdot: Protecting 'Funko' Brand, AI-Powered 'BrandShield' Knocks Itch.io Offline After Questionable Registrar Communications

Protecting 'Funko' Brand, AI-Powered 'BrandShield' Knocks Itch.io Offline After Questionable Registrar Communications Published on December 16, 2024 at 01:04AM Launched in 2013, itch.io lets users host and sell indie video games online — now offering more than 200,000 — as well as other digital content like music and comics. But then someone uploaded a page based on a major videogame title, according to Game Rant. And somehow this provoked a series of overreactions and missteps that eventually knocked all of itch.io offline for several hours... The page was about the first release from game developer 10:10 — their game Funko Fusion, which features characters in the style of Funko's long-running pop-culture bobbleheads. As a major brand, Funko monitors the web with a "brand protection" partner (named BrandShield). Interestingly, BrandShield's SaaS product "leverages AI-driven online brand protection," according to their site, to "detect...
Post a Comment
Read more